Medical Lasers

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Fig. 2. Effects of essential oil extracted from ZCN on melanogenesis in B16F10 cells. B16F10 cells were treated with ZCN (0.005–0.04%), L-ascorbic acid (0.25 mM), and kojic acid (0.5 mM). (A) Melanin content and (B) mushroom tyrosinase activity in B16F10 cells were measured as described in the Materials and methods. Each experiment was performed in triplicate, and the data represent means ± SD. p<0.05 (*), p<0.01 (**), and p<0.005 (***) versus non-treated control (A) or L-DOPA-treated control (B). *Data are presented as estimated means ± standard deviations.
Medical Lasers; Engineering, Basic Research, and Clinical Application 2018;7:62~68
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