Medical Lasers

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Fig. 3. In vivo rat skin reactions after invasive bipolar radiofrequency (RF) treatment. (A, B) Single-pass, invasive bipolar RF (VivaceTM; Shenb Co., Ltd., Seoul, Korea) treatment using 36 insulated microneedles in a 6 × 6 pattern generates well-demarcated oval zones of tissue coagulation (asterisks) in the dermis of in vivo female Sprague-Dawley rat skin at a frequency of 1 MHz, a RF conduction time of 200 msec, a microneedle penetration depth of 2 mm, and a power of (A) 50 W and (B) 70 W. (C, D) Meanwhile, single-pass, invasive bipolar RF treatment using insulated microneedles generates larger areas of tissue coagulation (asterisks) in the dermis at a frequency of 1 MHz, a RF conduction time of 500 msec, and a power of (C) 50 W and (D) 70 W. Hematoxylin and eosin stain, original magnification ×100.
Medical Lasers; Engineering, Basic Research, and Clinical Application 2020;9:12~24 https://doi.org/10.25289/ML.2020.9.1.12
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