Medical Lasers

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Fig. 4. Ex vivo human skin reactions after 532-nm and 1,064-nm microlens array (MLA)-type, picosecond laser treatment. (A, B) Single-pulse, 532-nm, picosecond laser (PicoPlus®; Lutronic Corp.) treatment at a 6-mm spot size, a pulse duration of 450 picoseconds, a fluence of 1.0 J/cm2, and a distance between the microlens and the skin of 48 mm generates cystic cavitation lesions (asterisks) and microscopic perinuclear vacuolar changes in the lower epidermis and papillary dermis in ex vivo human skin with Fitzpatrick skin type III. (C, D) Single-pulse, 1,064-nm, picosecond laser treatment at a 7-mm spot size, a pulse duration of 450 picoseconds, a fluence of 1.9 J/cm2, and a distance between the microlens and the skin of 31 mm generates the fractionated appearance of cystic cavitation lesions (asterisks) and perinuclear vacuolar changes in the lower epidermis and papillary dermis. Hematoxylin and eosin stain, original magnification (A, C) ×200, (B, D) ×400.
Medical Lasers; Engineering, Basic Research, and Clinical Application 2020;9:12~24 https://doi.org/10.25289/ML.2020.9.1.12
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