Medical Lasers; Engineering, Basic Research, and Clinical Application  
Partial Unilateral Lentiginosis Successfully Treated with a High-fluence 1,064-nm Q-switched Neodymium:Yttrium-Aluminum-Garnet Laser
Jun Ki Hong, Hye Sung Han, Sun Hye Shin, Kwang Ho Yoo
Department of Dermatology, Chung-Ang University Hospital, Seoul, Korea
Correspondence to: Kwang Ho Yoo
Department of Dermatology, Chung-Ang University Hospital, 102 Heukseok-ro, Dongjak-gu, Seoul 06973, Korea
Tel.: +82-2-6299-3179
Fax: +82-2-6299-1718
Received: March 15, 2021; Accepted: April 19, 2021; Published online: April 28, 2021.
© Korean Society for Laser Medicine and Surgery. All rights reserved.

Partial unilateral lentiginosis (PUL) is an unusual pigmentary disorder characterized by numerous lentigines on the skin, with onset usually during early childhood. It is characterized by unilateral segmental distribution with sharp margins in one or more dermatomes. Conventional laser treatments result in several adverse effects, such as mottled pigmentary changes (hyper or hypopigmentation), especially in people of Asian descent. A 57-year-old man with PUL on the neck was treated with a high-fluence 1,064-nm Q-switched (QS) neodymium-doped yttrium-aluminum-garnet (Nd:YAG) laser. After 20 treatment sessions, the lesions markedly improved without adverse effects or recurrence. We suggest that high-fluence 1,064-nm QS Nd:YAG laser treatment is an effective and safe modality for PUL.
Keywords: Partial unilateral lentiginosis; Neodymium:yttrium-aluminum-garnet laser

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