Medical Lasers; Engineering, Basic Research, and Clinical Application  
Treatment of an Atrophic Scar with Fractional Carbon Dioxide Laser-assisted Poly-L-lactic Acid Delivery
Wan Jin Kim1, Ha Rin Jung2, Sang Ju Lee3, Han Kyoung Cho1
1Department of Dermatology, Hanyang University Medical Center, Myongji Hospital, Goyang, Korea
2Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA
3Yonsei Star Skin & Laser Clinic, Seoul, Korea
Correspondence to: Han Kyoung Cho
Department of Dermatology, Hanyang University Medical Center, Myongji Hospital, 55 Hwasu-ro 14 beon-gil, Deogyang-gu, Goyang 10475, Korea
Tel.: +82-31-810-7050
Fax: +82-31-810-7057
E-mail: trpchk@hanmail.net
Received: July 12, 2021; Accepted: August 16, 2021; Published online: September 8, 2021.
© Korean Society for Laser Medicine and Surgery. All rights reserved.

Abstract
Scars can cause great psychological stress among patients. Currently, there are numerous topical agents, laser and surgical treatments available for skin rejuvenation and scar minimization. Laser-assisted drug delivery (LADD) is a treatment method that increases drug delivery by stimulating the skin physically and chemically to enhance the penetration of topical agents. This is one of the areas of great interest in the treatment of various skin diseases in addition to its use for cosmetic purposes. In particular, LADD is relatively non-invasive and has advantages in terms of accessibility and stability. Poly-L-lactic acid (PLLA) is a collagen stimulator known to gradually restore skin volume by inducing inflammation and fibroplasia. Herein, we report a case of treatment of an atrophic scar with fractional carbon dioxide laser-assisted PLLA delivery.
Keywords: Atrophic scar; Fractional carbon dioxide laser; Laser-assisted drug delivery; Poly-L-lactic acid


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