Medical Lasers

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eISSN 2288-0224

Table 2

List of outcomes and adverse events

Study (yr) Evaluation method Evaluation timing Result Reported adverse event
Choi et al. (2019) [21] NRS of loudness, duration, and annoyance, THI, Psychoacoustical matches of tinnitus loudness, and MML Immediately, 2 weeks after treatment No statistically significant differences between two groups No AEs observed
Dehkordi et al. (2015) [6] NRS of loudness, TSI, Psychoacoustical matches of tinnitus loudness Immediately No statistically significant differences between two groups Not reported
Mirvakili et al. (2014) [26] VAS of severity, THI Immediately, 3 months after treatment Short-term treatment of LLLT was effective, but its impact may be reduced over the time Not reported
Ngao et al. (2014) [27] VAS of annoyance, sleep disruption, depression, concentration, loudness, and pitch, THI Immediately Not significantly superior to placebo effect in improving tinnitus Not reported
Mollasadeghi et al. (2013) [28] VAS of loudness, THI, Psychoacoustical matches of tinnitus loudness Immediately, 3 months after treatment Short-term treatment of LLLT was effective, but an effect that was weakened after 3 months follow-up Not reported
Teggi et al. (2009) [7] VAS of loudness, THI, Psychoacoustical matches of pitch, loudness, and MML Immediately No efficacy as a therapeutic measure for tinnitus Not reported
Cuda and De Caria (2008) [19] THI Immediately The THI scores more significantly improved in the group receiving LLLT Not reported
Gungor et al. (2008) [5] VRS of loudness, duration, and annoyance 2 weeks after treatment The loudness, duration, and degree of annoyance of tinnitus were improved in LLLT group. No significant improvement was observed in the placebo laser group No AEs observed
Nakashima et al. (2002) [29] VRS of loudness, duration, and annoyance 1 week after treatment No significant difference was observed between two groups Sudden hearing loss and dizziness
Mirz et al. (1999) [30] VAS of loudness, annoyance, and attention involved, THI, TCSQ, BDI, STAI Immediately No statistically significant differences between two groups Not reported

NRS, numeric rating scale; THI, Tinnitus Handicap Inventory; MML, minimum masking levels; TSI, Tinnitus Severity Index; VAS, visual analogue scale; VRS, verbal rating scale; TCSQ, Tinnitus Coping Style Questionnaire; BDI, Beck Depression Inventory; STAI, State-Trait Anxiety Inventory; LLLT, low-level light therapy; AE, adverse effect.

Med Lasers 2022;11:195~200 https://doi.org/10.25289/ML.22.038
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