Fig. 2. Comparisons of skin grades at pretreatment and posttreatment. Mean value of skin grades was 17 (IQR: 16-19) at pretreatment and 14 (IQR: 14.00-15.25) at posttreatment. There was a statistically significant (p < 0.01) difference in skin grade between pretreatment and posttreatment.