Medical Lasers

pISSN 2287-8300
eISSN 2288-0224

Table 1

Data of selected laser therapy

Reference Title Therapy protocol Result
Lanzafame et al. (2013) [22] The growth of human scalp hair mediated by visible red light laser and LED sources in males Source: TOPHAT655 (helmet-type laser & LED array)
Wavelength: 655 nm
Period: 60 times for 16 wk, 25 min per times for the global scalp
Low level laser treatment for androgenetic alopecia is safe and effective, with a 35% increase in hair counts
Kim et al. (2013) [30] Low-level light therapy for androgenetic alopecia: a 24-week, randomized, double-blind, sham device-controlled multicenter trial Source: helmet-type laser & LED array
Wavelength: 630 nm, 660 nm, 650 nm
Period: every day for 24 wk, 18 min per times
LLLT group showed significantly higher hair density and improved mean hair diameter
Lanzafame et al. (2014) [31] The growth of human scalp hair in females using visible red light laser and LED sources Source: TOPHAT655 (helmet-type laser & LED array)
Wavelength: 655 nm
Period: 60 times for 16 wk, 25 min per times for the global scalp
Low level laser treatment for androgenetic alopecia is safe and effective, with a 37% increase in hair counts
Friedman and Schnoor (2017) [32] Novel approach to treating androgenetic alopecia in females with photobiomodulation (low-level laser therapy) Source: helmet-type LD & LED array
Wavelength: 650 nm
Period: 30 min per every other day for 17 wk
LLLT achieved a 51% increase (p < 0.001) in hair counts as compared with sham-treated control patients
Mai-Yi Fan et al. (2018) [33] Efficacy and safety of a low-level light therapy for androgenetic alopecia: a 24-week, randomized, double-blind, self-comparison, sham device-controlled trial Source: helmet-type LED array
Wavelength: 660 nm, 650 nm
Period: 3 times per wk for 24 wk, 30 min per times
LLLT-treated scalp had significantly greater hair coverage, hiar thickness, hair count and IGA than sham light-treated side at 12- and 24-week visits
Alhattab et al. (2020) [34] The effect of 1540-nm fractional erbium-glass laser in the treatment of androgenic alopecia Source: fractional erbium-glass laser
Wavelength: 1,540 nm
Period: 10 times at 2-wk intervals
Parameter: 7 mm tip, 6 mJ energy, 1 Hz frequency
Hair density and thickness were significantly increased in both males and females
Panchaprateep et al. (2019) [35] Quantitative proteomic analysis of dermal papilla from male androgenetic alopecia comparing before and after treatment with low-level laser therapy Source: helmet-type laser & LED array
Wavelength: 655 nm
Period: 24 wk, 25 min per every day
LLLT increased the dermal papilla and clinically improved hair diameter
Suchonwanit et al. (2019) [36] Low-level laser therapy for the treatment of androgenetic alopecia in Thai men and women: a 24-week, randomized, double-blind, sham device-controlled trial Source: helmet-type LD
Wavelength: 660 nm
Period: 3 times per wk for 24 wk, 20 min per session
The laser helmet outperformed in terms of increasing hair density and diameter, as well as showing a significantly greater improvement in global photographic assessment
Yoon et al. (2020) [37] Low-level light therapy using a helmet-type device for the treatment of androgenetic alopecia: a 16-week, multicenter, randomized, double-blind, sham device-controlled trial Source: helmet-type LD & LED array
Wavelength: 655 nm
Period: 56 times for 16 wk, 25 min per every other day
LLLT had a significant effect on enhancing hair density and thickness for males and females

LED, light emitting diode; LD, laser diode; LLLT, low-level laser therapy; IGA, investigator’s global assessment.

Med Lasers 2023;12:11~17 https://doi.org/10.25289/ML.23.008
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